Travis Ishikawa hit a game-winning, three-run walk-off home run off Michael Wacha in the bottom of the ninth inning, to help propel the San Francisco Giants past the St. Louis Cardinals, 6-3, in San Francisco on Thursday night, to win Game 5 of the National League Championship Series and advance to the World Series for the third time in the last five years.

St. Louis scored first, when Jon Jay doubled to left, on a ball that was misplayed by Ishikawa, allowing Tony Cruz to score, giving them a 1-0 lead in the top half of the third inning

San Francisco answered right back in the bottom half of the third inning, taking a 2-1 lead on a two-run home run by Joe Panik.

The Cardinals tied the game, 2-2, courtesy of a solo homer off the bat of Matt Adams in the top half of the fourth inning.

Later in the fourth inning, Tony Cruz followed Adams with a solo blast of his own, giving the Cardinals a 3-2 advantage.

With the Giants trailing 3-2 in the eighth inning, Michael Morse hit a game-tying, pinch-hit home run off Pat Neshek to even the score, 3-3.

That set-up the dramatic home run by Ishikawa, the first walk-off homer in NLCS history.

The Giants, who defeated the Cardinals, 4-games-to-1 in the NLCS, will face the Kansas City Royals in Game 1 of the 2014 World Series, beginning on Tuesday in Kansas City.

All video is courtesy of MLB.com.